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陈艳华

【来源: | 发布日期:2019-09-18 】

陈艳华

汉族,副研究员,理学博士,硕士生导师,入选北京市高校青年英才计划(2013年),中央民族大学高层次优秀人才(2019年)。

2003年于吉林大学取得学士学位,2006年于吉林大学取得硕士学位,2009年于北京协和医学院药物研究所取得博士学位,随后留所任助理研究员(至2014年7月),副研究员,硕士生导师。2019年6月以高层次优秀人才引进至中央民族大学。

任中国医师协会癌症代谢与治疗专业委员会委员,中国生物物理学会代谢组学分会理事。任Analyst、Frontiers in Pharmacology、Bioanalysis、Analytical letters等国际期刊同行评阅人。发表SCI收录论文30余篇;申请专利2项,软件著作权1项。获中国分析测试协会科学技术奖(CAIA奖)一等奖(第二完成人)。

通信地址:北京市海淀区中关村南大街27号 中央民族大学生物成像与系统生物学中心

邮编:100081

电子邮箱:201901007@muc.edu.cn

个人主页:https://www.researchgate.net/profile/Chen_Yanhua4

讲授课程

质谱分析的原理及应用:代谢组学中的质谱分析(北京协和医学院)

主要研究内容

代谢组学分析新方法及其在重大疾病中的应用研究;

定量代谢组学分析新方法研究;

药物代谢组学和药物体内代谢过程研究。

主持教学和科研项目

1.国家重点研发计划(234万):子任务负责人(2018-2022)

2.国家自然科学基金青年项目(25万):主持(2015-2017)

3.北京市高校青年英才计划(15万):主持(2013-2015)

4. 863计划项目-课题1(1021万):主要参与人(2014-2016)

5. 国家自然科学基金委重点项目(300万):主要参与人(2014-2018)

代表性科研论文

  1. Han Liao, Qingce Zang, Qinglin Lv, Yang Gao, Zitong Zhao, Jiuming He, Ruiping Zhang, Yongmei Song,Yanhua Chen*and Zeper Abliz.Development of methionine methylation profiling and relative quantification in human breast cancer cells based on metabolic stable isotope labeling.

    Analyst.2019, DOI: 10.1039/c9an00545e.(SCI二区)

  2. Xiaofei Yue, Jiuming He, Ruiping Zhang, Jing Xu, Zhi Zhou, Rui Zhang, Nan Bi, Zhonghua Wang, Chenglong Sun, Luhua Wang,Yanhua Chen*, Zeper Abliz* (Co-Corresponding author).Biotransformation-based metabolomics profiling method for determining and quantitating cancer-related metabolites.

    Journal of Chromatography A,2018, 1580, 80–89(SCI二区)

  3. Yang Gao,Yanhua Chen*, Xiaofei Yue, Jiuming He, Ruiping Zhang, Jing Xu, Zhi Zhou, Zhonghua Wang, Rui Zhang, Zeper Abliz*. Development of simultaneous targeted metabolite quantification and untargeted metabolomics strategy using dual-column liquid chromatography coupled with tandem mass spectrometry.

    Anal Chim Acta., 2018, 1037:369-379.(SCI二区)

  4. Yanhua Chen#, Zhi Zhou#, Wei Yang, Nan Bi, Jing Xu, Jiuming He, Ruiping Zhang, Lvhua Wang, Zeper Abliz*. Development of a Data-Independent Targeted Metabolomics Method for Relative Quantification Using Liquid Chromatography coupled with Tandem Mass Spectrometry.

    Anal. Chem., 2017, 89 (13) :6954-6962.(SCI一区)

  5. Yanhua Chen,Zeper Abliz*. Mass spectrometry in metabolomics: what lies ahead.

    Bioanalysis2017, 9(2): 155-157.

  6. Zhi Zhou,Yanhua Chen*,Jiuming He, Jing Xu, Ruiping Zhang, Yan Mao, Zeper Abliz. Systematic evaluation of serum and plasma collection on the endogenous metabolome.

    Bioanalysis 2017, 9:239-250.(SCI三区)

  7. Yanhua Chen#, Jing Xu#, Ruiping Zhang, Zeper Abliz*. Methods used to increase the comprehensive coverage of urinary and plasma metabolomes by MS.

    Bioanalysis. 2016, 8(9): 981-997.

  8. Yanhua Chen, Guoqing Shen, Ruiping Zhang, Jiuming He, Yi Zhang, Jing Xu, Wei Yang, Xiaoguang Chen, Yongmei Song, Zeper Abliz*. Combination of Injection Volume Calibration by Creatinine and MS Signals’Normalization to Overcome Urine Variability in LC-MS-Based Metabolomics Studies.

    Anal. Chem.,2013, 85: 7659−7665.(SCI一区)

  9. Yanhua Chen, Jing Xu, Ruiping Zhang, GuoqingShen, Yongmei Song, Jianghao Sun, Jiuming He, Qimin Zhan, Zeper Abliz*. Assessment of data pre-processing methods for LC-MS/MS-based metabolomics of uterine cervix cancer.

    Analyst, 2013, 138: 2669-2677(SCI二区)

  10. Jing Xu#,Yanhua Chen#,(Co-first author)Ruiping Zhang, Yongmei Song, Jianzhong Cao, Nan Bi, Jingbo Wang, Jiuming He, Jinfa Bai, Lijia Dong, Luhua Wang, Qimin Zhan, Zeper Abliz*. Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers.

    Mol Cell Proteomics, 2013, 12: 1306-1318.(SCI二区)

  11. 陈艳华,张瑞萍,宋咏梅,董立佳,詹启敏,再帕尔·阿不力孜*.基于快速高分辨液相色谱串联质谱技术的代谢组学尿液分析方法的建立.

分析化学, 2011, 39(2): 173-177.

  1. Yanhua Chen, Ruiping Zhang, Yongmei Song, Jiuming He, Jianghao Sun, Jinfa Bai, Zhuoling An, Lijia Dong, Qimin Zhan,Zeper Abliz*.

Analyst,2009, 134:2003–2011.(SCI二区)

  1. 陈艳华,卜凤泉,胡秀丽,刘志强,刘忠英*,刘景英,周秋丽.

    光谱学与光谱分析, 2007, 27(10):2079-2082.