崔晓杰
汉族，讲师。
教育经历：
2015.6-2017.7 法国巴黎居里研究所，UMR3244（Dr. Alain Nicolas组) 博士后
2014.7-2015.5 北京大学化学与分子工程学院（袁谷教授组） 研究助理
2009.9-2014.7 北京大学化学与分子工程学院（化学生物学） 博士
2005.9-2009.7 山东大学化学与化工学院（化学基地班） 学士
通信地址：北京市海淀区中关村南大街27号 中央民族大学生命与环境科学学院
邮编：100081
电子邮箱：xiaojiecui@muc.edu.cn
讲授课程
有机化学，化学生物学，有机化学实验
主要研究内容
1. 核酸四链体高级结构（G-四链体、i-motif等）的性质和表征；
2. 植物天然产物分子筛选、衍生物设计及其对核酸四链体结构的识别调控。
代表作
1. Yun Zhang, Junliu Huang, Kainan Yu and Xiaojie Cui*, “G-Quadruplexes Formation by the C9orf72 Nucleotide Repeat Expansion d(GGGGCC)(n) and Conformation Regulation by Fangchinoline”, Molecules, 2023, 28, 4671.
2. Yun Zhang, Xinao Ma, Jingtian Zhang, Feixian Luo, Wenshu Wang and Xiaojie Cui*, “Design of a High-Sensitivity Dimeric G-Quadruplex/Hemin DNAzyme Biosensor for Norovirus Detection”, Molecules, 2021, 26, 7352.
3. Xiaojie Cui*, Han Chen, Qiang Zhang, Ming Xu, Gu Yuan and Jiang Zhou*, “Exploration of the structure and Recognition of a G-quadruplex in the her2 Proto-oncogene Promoter and Its transcriptional Regulation”, Sci. Rep., 2019, 9, 3966.
4. Aurèle Piazza#, Xiaojie Cui#, Michael Adrian, Frédéric Samazan, Brahim Heddi, Anh Tuân Phan* and Alain Nicolas*, “Non-Canonical G-quadruplexes Cause the hCEB1 Minisatellite Instability in Saccharomyces cerevisiae”, # co-first author, eLife, 2017, 6, e26884.
5. Xiaojie Cui, Qiang Zhang, Han Chen, Jiang Zhou, and Gu Yuan*, “ESI Mass Spectrometric Exploration of Selective Recognition of G-Quadruplex in c-myb Oncogene Promoter Using a Novel Flexible Cyclic Polyamide”, J. Am. Soc. Mass Spectrom., 2014, 25, 684.
6. Xiaojie Cui, Sen Lin, Jiang Zhou and Gu Yuan*, “Investigation of non-covalent interaction
of natural flexible cyclic molecules with telomeric RNA G-quadruplexes by electrospray ionization mass spectrometry”, Rapid Commun. Mass Spectrom., 2012, 26 , 1803.
7. Xiaojie Cui, Sen Lin and Gu Yuan*, “Spectroscopic probing of recognition of the G-quadruplex in c-kit promoter by small-molecule natural products”, Int. J. Biol. Macromol., 2012, 50, 996.
8. Xiaojie Cui andGu Yuan*, “Formation and recognition of G-quadruplex in promoter of c-myb oncogene by electrospray ionization mass spectrometry”, J. Mass Spectrom., 2011, 46, 849.
9. Qiang Zhang, Xiaojie Cui, Sen Lin, Jiang Zhou, and Gu Yuan*, “Convenient Method for the Synthesis of a Flexible Cyclic Polyamide for Selective Targeting of c-myb G-quadruplex DNA”, Org. Lett.,2012, 14, 6126.
10. Han Chen, Haitao Long, Xiaojie Cui, Jiang Zhou, Ming Xu and Gu Yuan*, “Exploring the Formation and Recognition of an Important G-Quadruplex in a HIF1-alpha Promoter and Its Transcriptional Inhibition by a Benzo-c-phenanthridine Derivative”, J. Am. Chem. Soc., 2014, 136, 258.
11. Sen Lin, HuipingGu, Ming Xu, Xiaojie Cui, Youyi Zhang, Wei Gao and Gu Yuan, “The Formation and Stabilization of a Novel G-Quadruplex in the 5 '-Flanking Region of the Relaxin Gene”, Plos One, 2012, 7, e31201.
