Zhi ZHOU
Position: Lecturer, Master's Supervisor
Address: Research Center for Biological Imaging and Systems Biology, Minzu University of China, No. 27, Zhongguancun South Street, Haidian District, Beijing
Postal Code: 100081
Email: zhouzhi@muc.edu.cn
Graduated in July 2017 with a Ph.D. in Science from the Institute of Medicinal Chemistry, Chinese Academy of Medical Sciences & Peking Union Medical College.
Teaching
Research Focus
Development of new metabolomics methods based on mass spectrometry technology and research on disease biomarkers.
Research Projects Led and Participated In
Youth Science Fund Project, National Natural Science Foundation of China
“New Method for In Situ Characterization of Whole Zebrafish Metabolomics Based on Mass Spectrometry Imaging Technology and Its Application in the Heterogeneity of Esophageal Cancer” (Project No.: 82003714)
(Principal Investigator)
National Major Research Instrument Development Program
“Development of Metabolite Imaging and In Situ Mass Spectrometry Analysis Device” (Project No.: 21927808)
(Participant)
Youth Faculty Research Capacity Enhancement Program, Minzu University of China
“Research on the Aromatic Amino Acid Metabolic Signature Analysis Method for Tumors Based on Mass Spectrometry Imaging Technology” (Project No.: 2020QNPY89)
(Principal Investigator, Completed)
National Key R&D Program, Modernization of Traditional Chinese Medicine
“Research on Ethnic Medicine Diagnosis and Treatment Plans for Major Diseases and Safety & Efficacy Evaluation of Classical Formulas” (Project No.: 2017YFC1704000)
(Participant, Completed)
Key Project, National Natural Science Foundation of China
“Research on New Methods for Rapid Screening and Early Diagnosis of Esophageal Cancer Using Integrated Metabolomics and Mass Spectrometry Imaging and Detection Technologies” (Project No.: 21335007)
(Participant, Completed)
National High-Tech Research and Development Program (863 Program)
“Development of Key Technologies for Ultra-Sensitive, High-Coverage Metabolomics Quantitative Analysis” (Project No.: SS2014AA021101)
(Participant, Completed)
Youth Science Fund Project, National Natural Science Foundation of China
“Research on Quantitative Methylation Metabolomics Using Isotope Metabolic Labeling and Quantitative Metabolomics” (Project No.: 21405179)
(Participant, Completed)
2015 Peking Union Medical College Young Scientific Research Fund Student Innovation Project
“Research on Tissue Metabolomics Sample Preparation Using Solid-Phase Microextraction Technology” (Project No.: 3332015045)
(Principal Investigator, Completed)
Representative Achievements
Journal Papers:
1. Yue Sun, Zhi Zhou*, Bing Xie, Zhonghua Wang, Zeper Abliz*. Spatially Resolved Metabolomics Method for Mapping the Global Molecular Landscape of Whole-Body Zebrafish (Danio rerio) Using Ambient Mass Spectrometry Imaging. Analytical Chemistry, 2023, 95: 9165-7172 (SCI 化学1区 top类)
2. Yanhua Chen#, Zhi Zhou#, Wei Yang, Nan Bi, Jing Xu, Jiuming He, Ruiping Zhang, Lvhua Wang, Zeper Abliz*, Development of a Data-Independent Targeted Metabolomics Method for Relative Quantification Using Liquid Chromatography Coupled with Tandem Mass Spectrometry, Analytical Chemistry, 2017, 89(13): 6954-6962 (SCI 化学1区 top类)
3. Zhi Zhou, Bin Xie, Chen Zhang, Lulu Chen, Zhonghua Wang, Yanhua Chen, Zeper Abliz*, Multidimensional molecular differences between artificial cultivated and wild Artemisia rupestris L. based on metabolomics–transcriptomics integration strategy. Industrial crops & Products, 2021, 170: 113732 (SCI 农林科学1区 top类)
4. Zhi Zhou, Yanhua Chen*, Yang Gao, Nan Bi, Xiaofei Yue, Jiuming He, Ruiping Zhang, Luhua Wang, Zeper Abliz*, Development of a high-coverage metabolome relative quantitative method for large-scale sample analysis, Analytica Chimica Acta, 2020, 1109: 44-52 (SCI 化学2区 top类)
5. Zhi Zhou, Yanhua Chen*, Jiuming He, Jing Xu, Ruiping Zhang, Yan Mao, Zeper Abliz, Systematic evaluation of serum and plasma collection on the endogenous metabolome, Bioanalysis, 2017, 9(3): 239-250 (SCI 3区)
