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李鲜婵

【来源: | 发布日期:2019-03-01 】

李鲜婵

汉族,教授,理学博士,入选中组部千人计划青年项目(2019年,全额资助),中央民族大学高层次优秀人才(2018年)。

2004年于北京大学取得学士学位,2009年于中科院化学所取得博士学位,随后留所任助理研究员至2013年4月。2013年4月至2015年4月在瑞典查尔姆斯理工大学从事博士后研究(合作导师Andrew G. Ewing教授)。2015年4月至2018年6月在瑞典哥德堡大学任researcher。

任J. Am. Chem. Soc.、PNAS、Angew. Chem. Int. Ed.、Anal. Chem.、Analyst、Electrochem. Commun.、Anal. Bioanal. Chem.等国际著名期刊同行评阅人。发表SCI收录论文近40篇;发明专利3项(含1项国际PCT专利);英文专著1章。

通信地址:北京市海淀区中关村南大街27号 中央民族大学生物成像与系统生物学中心

邮编:100081

电子邮箱:xianchan.li@muc.edu.cn

个人主页:https://www.researchgate.net/profile/Xianchan_Li/research

讲授课程

表面与胶体化学

主要研究内容

神经化学信号转导的分析化学研究;

生物纳米颗粒的分析化学研究;

重大脑疾病分子机制及药物干预机制研究。

主持教学和科研项目

1.国家自然科学基金面上项目(68万):主持(2020-2023)

2.国家千人计划青年项目(300万):主持(2019-)

3.国家自然科学青年基金项目(22万):主持(2011-2013)

4.国家自然科学基金委重点项目(300万):主要参与人(2012-2016)

5.国家自然科学基金委重大国际合作研究项目(220万):主要参与人(2011-2013)

代表性科研论文

  1. Tongfang Xiao,Xianchan Li,(Co-first authors)Huan Wei, Wenliang Ji, Qingwei Yue, Ping Yu, Lanqun Mao*In Vivo Monitoring of Oxygen Fluctuation Simultaneously at Multiple Sites of Rat Cortex during Spreading Depression

    Anal. Chem.2018, 90, 13783-13789.(SCI一区)

  2. Amir S Mohammadi,Xianchan Li,(Co-first authors), Andrew G. Ewing*.Mass Spectrometry Imaging Suggests That Cisplatin Affects Exocytotic Release by Alteration of Cell Membrane Lipids.

    Anal. Chem.2018,90, 8509-8516.(SCI一区)

  3. Xianchan Li, Lin Ren, Johan Dunevall, Daixin Ye, Henry S. White, Martin A. Edwards*, Andrew G. Ewing*.On the Nanopore Opening at Flat and Nano-Tip Conical Electrodes during Vesicle Impact Electrochemical Cytometry.

    ACS Nano,2018,12, 3010-3019.(SCI一区)

  4. Xianchan Li, Johan Dunevall, Andrew G. Ewing*.

    Electrochemical Quantification of Transmitter Concentration in Single Nanoscale Vesicles Isolated from PC12 Cells.

    Faraday Discussions, 2018, 210, 353-364.(SCI二区)

  5. Xianchan Li, Johan Dunevall, Lin Ren, Andrew G. Ewing*.Mechanistic Aspects of Vesicle Opening during Analysis with Vesicle Impact Electrochemical Cytometry.

    Anal. Chem.2017, 89, 9416−9423.(SCI一区)

  6. Nhu T.N. Phan,Xianchan Li, Andrew G. Ewing*.Measurement of synaptic vesicles: from the chemical content to structure and activity using cellular electrochemistry and nanoscale molecular imaging.

    Nature Reviews Chemistry, 2017, 1, 0048.

  7. Xianchan Li†, Johan Dunevall†, Andrew G. Ewing*.Quantitative Chemical Measurements of Vesicular Transmitters with Electrochemical Cytometry.

    Acc. Chem. Res.2016, 49, 2347-2354. (SCI一区)

  8. Xianchan Li, Johan Dunevall, Andrew G. Ewing*.Using Single-Cell Amperometry to Reveal How Cisplatin Treatment Modulates the Release of Catecholamine Transmitters during Exocytosis

    Angew. Chem. Int. Ed.2016, 55, 9041-9044. (IF=11.954) (SCI一区)

    CoverAngew. Chem. Int. Ed.2016, 55, 9098.

  9. Xianchan Li, Amir Saeid Mohammadi, Andrew G. Ewing*.

    Single Cell Amperometry Reveals Curcuminoids Modulate the Release of Neurotransmitters during Exocytosis from PC12 Cells

    J. Electroanal. Chem.2016, 781, 30-35.(SCI二区)

  10. Xianchan Li†, Soodabeh Majdi†, Johan Dunevall, Hoda Fathali, Andrew G. Ewing*. Quantitative Measurement of Transmitters in Individual Vesicles in the Cytoplasm of Single Cells with Nanotip Electrodes

    Angew. Chem. Int. Ed.2015, 54, 11978-11982. (SCI一区)

  11. Xianchan Li, Ping Yu, Lifen Yang, Fuyi Wang, Lanqun Mao*.An Electrochemical Method for Investigation of Conformational Flexibility of Active Sites of Trametes versicolor Laccase Based on Sensitive Determination of Copper Ion with Cysteine-Modified Electrodes.

    Anal.Chem.2012, 84, 9416-9421.(SCI一区)

  12. Xianchan Li, Lingzhi Zhao, Zhenling Chen, Yuqing Lin, Ping Yu, Lanqun Mao*. Continuous Electrochemical Monitoring of Extracellular Lactate Production from Neonatal Rat Cardiomyocytes following Myocardial Hypoxia.

Anal.Chem.2012, 84, 5285-5291.(SCI一区)

  1. Xianchan Li, Wei Zheng, Limin Zhang, Ping Yu, Yuqing Lin, Lei Su, Lanqun Mao*. Effective Electrochemical Method for Investigation of Hemoglobin Unfolding Based on the Redox Property of Heme Groups at Glassy Carbon Electrodes.

    Anal.Chem.2009, 81, 8557-8563.(SCI一区)